Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell decline

13 Oct 1998

Abstract excerpt

Evolution of HIV-1 env sequences was studied in 15 seroconverting injection drug users selected for differences in the extent of CD4 T cell decline. The rates of increase of either sequence diversity at a given visit or divergence from the first seropositive visit were both higher in progressors than in nonprogressors. Viral evolution in individuals with rapid or moderate disease progression showed selection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evolution and Genetic Dynamics
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9770526
DOI: 10.1073/pnas.95.21.12568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell declinePMID 9770526Read ↗

Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function.Semantic proximity Read ↗

HIV-1 evolution in gag and env is highly correlated but exhibits different relationships with viral load and the immune response.Semantic proximity Read ↗

Slower evolution of human immunodeficiency virus type 1 quasispecies during progression to AIDS.Semantic proximity Read ↗

Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection.Semantic proximity Read ↗

Evolution of human immunodeficiency virus type 1 envelope sequences in infected individuals with differing disease progression profiles.Semantic proximity Read ↗

Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects.Semantic proximity Read ↗

Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression.Semantic proximity Read ↗

HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study.Semantic proximity Read ↗

Phylogenetic evidence of HIV-1 sequence evolution in subjects with persistent low-level viraemia.Semantic proximity Read ↗

Immune-mediated positive selection drives human immunodeficiency virus type 1 molecular variation and predicts disease duration.Semantic proximity Read ↗

Virus-Host Gene Interactions Define HIV-1 Disease Progression.Semantic proximity Read ↗

Deep Profiling Identifies Selection of Nonsynonymous Amino Acid Substitutions in HIV-1 Envelope During Early Infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.