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Article

Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression.

PLoS computational biology - 1 Dec 2008

Lee Ha Youn, Perelson Alan S, Park Su-Chan, Leitner Thomas

Abstract excerpt

Quantifying the dynamics of intrahost HIV-1 sequence evolution is one means of uncovering information about the interaction between HIV-1 and the host immune system. In the chronic phase of infection, common dynamics of sequence divergence and diversity have been reported. We developed an HIV-1 sequence evolution model that simulated the effects of mutation and fitness of sequence variants. The amount of...

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Identifiers

PMID: 19079613
DOI: 10.1371/journal.pcbi.1000240
PMCID: PMC2602878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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