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Article

HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study.

The Journal of infectious diseases - 1 Apr 2008

Gottlieb Geoffrey S, Heath Laura, Nickle David C, Wong Kim G, Leach Stephanie E, Jacobs Benjamin, Gezahegne Surafel, van 't Wout Angélique B, Jacobson Lisa P, Margolick Joseph B, Mullins James I

Abstract excerpt

Understanding the characteristics of human immunodeficiency virus (HIV) necessary for infection in a new host is a critical goal for acquired immunodeficiency syndrome (AIDS) research. We studied the characteristics of HIV-1 envelope genes in 38 men in the Multicenter AIDS Cohort Study cohort before seroconversion. We found a range of diversity (0.2%-5.6% [median, 0.86%]), V1-V2 loop length (58-93 aa), and...

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Share to CD4 Lymphocyte Count
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosylation

Share to HIV Infections

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Share to Receptors, CCR5

Share to Sequence Homology

Source

Open in PubMed Open full text

Identifiers

PMID: 18419538
DOI: 10.1086/529206
PMCID: PMC3419593

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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