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Article

Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function.

Journal of virology - 1 Mar 1997

McDonald R A, Mayers D L, Chung R C, Wagner K F, Ratto-Kim S, Birx D L, Michael N L

Abstract excerpt

We examined the relationship between env sequence variation and disease progression in 10 human immunodeficiency virus type 1 (HIV-1)-seropositive subjects selected from a longitudinal cohort receiving zidovudine therapy. Five subjects were chosen for stable clinical status and CD4 counts (slow progressors), and five were selected for rapid clinical deterioration and CD4 count decline (rapid progressors). The...

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Identifiers

PMID: 9032317
DOI: 10.1128/JVI.71.3.1871-1879.1997
PMCID: PMC191257

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Source receipt: pubmed, retrieved 7 Sept 2026.

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