Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function.

Journal of virology - 1 Mar 1997

McDonald R A, Mayers D L, Chung R C, Wagner K F, Ratto-Kim S, Birx D L, Michael N L

Abstract excerpt

We examined the relationship between env sequence variation and disease progression in 10 human immunodeficiency virus type 1 (HIV-1)-seropositive subjects selected from a longitudinal cohort receiving zidovudine therapy. Five subjects were chosen for stable clinical status and CD4 counts (slow p...

Topics

Base Sequence
Cohort Studies
DNA, Viral
Disease Progression
Evolution, Molecular
Genes, env
Genetic Variation
HIV Seropositivity
HIV-1
Humans
Longitudinal Studies
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 9032317
DOI: 10.1128/JVI.71.3.1871-1879.1997
PMCID: PMC191257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9032317-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function.PMID 9032317Read ↗

In vivo sequence variability of human immunodeficiency virus type 1 envelope gp120: association of V2 extension with slow disease progression.Semantic proximity Read ↗

Slower evolution of human immunodeficiency virus type 1 quasispecies during progression to AIDS.Semantic proximity Read ↗

Nucleotide and amino acid mutations in human immunodeficiency virus corresponding to CD4+ decline.Semantic proximity Read ↗

Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell declineSemantic proximity Read ↗

Disease progression and evolution of the HIV-1 env gene in 24 infected infants.Semantic proximity Read ↗

Evolution of human immunodeficiency virus type 1 envelope sequences in infected individuals with differing disease progression profiles.Semantic proximity Read ↗

Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection.Semantic proximity Read ↗

Relationship of human immunodeficiency virus type 1 sequence heterogeneity to stage of disease.Semantic proximity Read ↗

HIV-1 evolution in gag and env is highly correlated but exhibits different relationships with viral load and the immune response.Semantic proximity Read ↗

Long-term intrapatient viral evolution during HIV-2 infection.Semantic proximity Read ↗

Sequence variability in human immunodeficiency viruses: pattern and process in viral evolution.Semantic proximity Read ↗

Immune-mediated positive selection drives human immunodeficiency virus type 1 molecular variation and predicts disease duration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.