Article
Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects.
Retrovirology - 15 Jan 2009
Canducci Filippo, Marinozzi Maria Chiara, Sampaolo Michela, Berrè Stefano, Bagnarelli Patrizia, Degano Massimo, Gallotta Giulia, Mazzi Benedetta, Lemey Philippe, Burioni Roberto, Clementi Massimo
Abstract excerpt
The characteristics of intra-host human immunodeficiency virus type 1 (HIV-1) env evolution were evaluated in untreated HIV-1-infected subjects with different patterns of disease progression, including 2 normal progressor [NP], and 5 Long term non-progressor [LTNP] patients. High-resolution phylogenetic analysis of the C2-C5 env gene sequences of the replicating HIV-1 was performed in sequential samples collected...
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