Article
Phylogenetic evidence of HIV-1 sequence evolution in subjects with persistent low-level viraemia.
Antiviral therapy - 1 Jan 2015
Vardhanabhuti Saran, Taiwo Babafemi, Kuritzkes Daniel R, Eron Joseph J, Bosch Ronald J
Abstract excerpt
BACKGROUND: Persistent low-level viraemia (LLV) during the treatment of antiretroviral therapy (ART) is associated with emergent drug resistance mutation (DRM); however, insight into its driver is limited. The objectives were to study HIV-1 pol sequence evolution in subjects with persistent LLV and evaluate factors associated with sequence changes. METHODS: HIV-1 pol sequences from 54 treatment-naive subjects...
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