Article
Virus-Host Gene Interactions Define HIV-1 Disease Progression.
Current topics in microbiology and immunology - 1 Jan 2000
Monaco Daniela C, Ende Zachary, Hunter Eric
Abstract excerpt
In this chapter, we will review recent research on the virology of HIV-1 transmission and the impact of the transmitted virus genotype on subsequent disease progression. In most instances of HIV-1 sexual transmission, a single genetic variant, or a very limited number of variants from the diverse viral quasi-species present in the transmitting partner establishes systemic infection. Transmission involves both...
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