Article
Temporal restriction of MyoD induction and autocatalysis during Xenopus mesoderm formation.
Developmental biology - 15 Oct 1998
Steinbach O C, Ulshöfer A, Authaler A, Rupp R A
Abstract excerpt
In Xenopus, the activation of the myogenic determination factors MyoD and Myf-5 in the muscle-forming region of the embryo occurs in response to mesoderm-inducing factors (MIFs). Different members of the FGF, TGF-beta, and Wnt protein families have been implicated in this process, but how MIFs induce the myogenic regulators is not known. For MyoD, the induction process may serve to locally stabilize a transient...
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