Article
msd is required for mesoderm induction in mice.
Development (Cambridge, England) - 1 May 1994
Holdener B C, Faust C, Rosenthal N S, Magnuson T
Abstract excerpt
Mesoderm induction is fundamental for establishing the basic body plan of the vertebrate embryo and mutations are critical for dissecting this process. Mouse embryos lacking msd (mesoderm deficiency) do not produce mesoderm but have well-defined extraembryonic and thickened embryonic ectoderm. Distribution of transcripts indicate that temporal regulation of gene expression relevant to gastrulation has begun but...
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