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Mouse mammary tumor virus (MMTV), a retrovirus that exploits the immune system. Genetics of susceptibility to MMTV infection.

Medicina - 1 Jan 1997

Ross S R, Dzuris J L, Golovkina T V, Clemmons W C, van den Hoogen B

Abstract excerpt

All animals, including humans, show differential susceptibility to infection with viruses. Study of the genetics of susceptibility or resistance to specific pathogens is most easily studied in inbred mice. We have been using mouse mammary tumor virus (MMTV), a retrovirus that causes mammary tumors in mice, to study virus/host interactions. These studies have focused on understanding the mechanisms that determine...

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PMID: 9567342

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