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Article

Epitopes of human chorionic gonadotropin and their relationship to immunogenicity and cross-reactivity of beta-chain mutants.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Sept 1998

Porakishvili N, Jackson A M, de Souza J B, Dalla Chiesa M, Roitt I M, Delves P J, Lund T

Abstract excerpt

PROBLEM: Human chrionic gonadotropin (hCG) is a placental glycoprotein hormone, a heterodimeric molecule, consisting of alpha and beta chains. It induces the synthesis of progesterone, which is essential for the maintenance of the fertilized egg. Antibodies directed against hCG can, therefore, pr...

Topics

Animals
Antibodies, Monoclonal
Chorionic Gonadotropin
Chorionic Gonadotropin, beta Subunit, Human
Cross Reactions
DNA
Epitopes
Humans
Luteinizing Hormone
Mice
Mutagenesis, Site-Directed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Protein Folding

Source

Identifiers

PMID: 9764366
DOI: 10.1111/j.1600-0897.1998.tb00414.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9764366-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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