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Article

Human chorionic gonadotropin beta-subunit affects the folding and glycosylation of alpha-cys mutants.

Endocrine journal - 1 Oct 2000

Furuhashi M, Suganuma N

Abstract excerpt

Human chorionic gonadotropin (hCG) is a member of a family of heterodimeric glycoprotein hormones that contain a common alpha-subunit but differ in their hormone-specific beta-subunits. Both subunits have five and six disulfide bonds, respectively, which consist of cystine knot structure. It is evident from numerous studies that the structure of beta-subunits is rigid, whereas that of alpha-subunit is flexible...

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Identifiers

PMID: 11200939
DOI: 10.1507/endocrj.47.583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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