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Article

A novel four-amino acid determinant defines conformational freedom within chorionic gonadotropin beta-subunits.

Biochemistry - 10 Apr 2007

Wilken Jason A, Bedows Elliott

Abstract excerpt

On the basis of apparent molecular mass heterogeneity following reducing versus nonreducing SDS-PAGE, we determined that the beta-subunit of macaque (Macaca fascicularis) chorionic gonadotropin (mCG-beta) is more conformationally constrained than the beta-subunit of human chorionic gonadotropin (hCG-beta). The amino acid sequences of these two subunits are 81% identical. To determine the conformational variance...

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Identifiers

PMID: 17358049
DOI: 10.1021/bi602449d
PMCID: PMC2597539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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