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Article

Human chorionic gonadotropin as a target for cancer vaccines.

Oncology reports - 1 Jan 2000

Triozzi P L, Stevens V C

Abstract excerpt

Human chorionic gonadotropin (hCG) is expressed by common cancers and may play a role in cell transformation as well as angiogenic, metastatic, and immune escape phenomena that are central to cancer progression. Clinical trials with a vaccine targeting the carboxy-terminal peptide of -hCG have indicated that tolerance to this oncofetal antigen can be broken. Humoral responses that may modulate the biologic...

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PMID: 9864394

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