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Article

On the role of the invariant glutamine at position 54 in the human choriogonadotropin beta subunit.

Molecular and cellular biochemistry - 27 Jul 1994

Huang J, Puett D

Abstract excerpt

The twelve Cys and eight of the non-Cys residues are invariant in the glycoprotein hormone beta subunits from a variety of mammalian species. beta-Gin-54 of human lutropin (hLH) and choriogonadotropin (hCG) is one of these invariant amino acid residues. A single A-->G mutation in the LH beta gene of a patient presenting with hypogonadism resulted in the replacement of Gin-54 with Arg [1]. The authors also...

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Identifiers

PMID: 7531278
DOI: 10.1007/BF00926079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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