Article
Acquired resistance of a mammalian cell line to hypoxia-reoxygenation through cotransfection of Kir6.2 and SUR1 clones.
Laboratory investigation; a journal of technical methods and pathology - 1 Sept 1998
Jovanovic A, Jovanovic S, Carrasco A J, Terzic A
Abstract excerpt
Reoxygenation after transient hypoxia is a common clinical condition that often causes greater tissue damage than persistent hypoxia itself. This warrants the development of a means to protect cells against hypoxia-reoxygenation injury. Adenosine triphosphate (ATP)-sensitive K+ (KATP) channels ha...
Topics
- Animals
- COS Cells
- Calcium
- Genetic Predisposition to Disease
- Glyburide
- Glycosyltransferases
- Hypoxia
- Intracellular Membranes
- Membrane Proteins
- Potassium Channel Blockers
- Potassium Channels
- Potassium Channels, Inwardly Rectifying
- Reperfusion Injury
- Repressor Proteins
- Saccharomyces cerevisiae Proteins
- Transfection