Article
Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte.
Circulation - 14 Apr 1998
Nakano M, Knowlton A A, Dibbs Z, Mann D L
Abstract excerpt
BACKGROUND: Previous studies in isolated cardiac myocytes have shown that tumor necrosis factor (TNF)-alpha provokes increased expression of 27- and 70-kD stress proteins as well as manganese superoxide dismutase, suggesting that TNF-alpha might play a role in mediating stress responses in the heart. METHODS AND RESULTS: To determine whether TNF-alpha stimulation would protect isolated cardiac myocytes against...
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