Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality.

doi:10.1016/0922-4106(94)90146-5

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Article

Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality.

European journal of pharmacology - 15 Feb 1994

Cik M, Chazot P L, Stephenson F A

Abstract excerpt

Transient expression of wild-type N-methyl-D-aspartate, NMDAR1-1a/NMDAR2A heteromeric receptors, in mammalian cells yields cell death which was prevented by the inclusion of NMDA receptor antagonists in the cell culture media post-transfection. Transient expression of mutant NMDAR1-1a (N598Q)/NMD...

Topics

2-Amino-5-phosphonovalerate
Calcium
Cell Death
Cell Line
Humans
Kynurenic Acid
Mutation
Receptors, N-Methyl-D-Aspartate
Transfection

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