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Article

Sensitivity of KATP channels to cellular metabolic disorders and the underlying structural basis.

Acta pharmacologica Sinica - 1 Jan 2016

Li Chun-gang, Cui Wen-yu, Wang Hai

Abstract excerpt

AIM: ATP-sensitive potassium (KATP) channels formed by a combination of SUR/Kir6.x subunits play a crucial role in protection against hypoxic or ischemic injuries resulting from cell metabolic disorders. In this study we investigated the effects of Na-azide, a metabolic inhibitor, on KATP channels expressed in Xenopus oocytes, and explored the structure basis for their sensitivity to cell metabolic disorders....

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Identifiers

PMID: 26725741
DOI: 10.1038/aps.2015.134
PMCID: PMC4722982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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