Inhibition of voltage-dependent Na+ current in cell-fusion hybrids containing activated c-Ha-ras.

doi:10.1007/BF01872890

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Article

Inhibition of voltage-dependent Na+ current in cell-fusion hybrids containing activated c-Ha-ras.

The Journal of membrane biology - 1 Feb 1990

Estacion M

Abstract excerpt

The electrophysiological properties of EJ (human bladder carcinoma), GM2291 (human fetal lung fibroblast), and of three hybrid cell lines obtained from their cell fusion were investigated using the patch-clamp technique. GM2291 cells, which are nontumorigenic, express voltage-dependent Na+ channe...

Topics

Cell Line
Fibroblasts
Gene Expression Regulation
Genes, ras
Humans
Hybrid Cells
Membrane Potentials
Phenotype
Signal Transduction
Sodium Channels
Tumor Cells, Cultured
Urinary Bladder Neoplasms

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