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Isolated human Fos promoter in plasmid DNA is overactive

2024-10-11

Abstract excerpt

Changes in intracellular concentrations of Na + and K + are shown to alter Fos gene expression. Here, we obtained a genetic construct encoding TurboGFP-dest1 gene under control of the human Fos promoter (−549; +155) and studied its expression in HEK293T. Amplification of the Fos promoter sequence from genomic DNA was only efficient in the presence of Li + ions. Ouabain and medium with replacement of Na + w...

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Identifiers and source

Literature Corpus work
40af1543-7b05-5ec6-81c3-efe1efe7e473
DOI
10.1101/2024.10.11.617784
Open publication

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