Article
Intracellular localization and conformational state of transglutaminase 2: implications for cell death.
PloS one - 1 Jul 2009
Gundemir Soner, Johnson Gail V W
Abstract excerpt
Transglutaminase 2 (TG2) is a multifunctional enzyme that has guanine nucleotide binding and GTP hydrolyzing activity in addition to its transamidating function. Studies show that TG2 is a player in mediating cell death processes. However, there is far from a consensus about the role of this enzyme in cell death processes as it appears to be dependent upon the cell type, stimuli, subcellular localization and...
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