Article
Pore loop-mutated rat KIR6.1 and KIR6.2 suppress KATP current in rat cardiomyocytes.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2004
van Bever Laurianne, Poitry Serge, Faure Cécile, Norman Robert I, Roatti Angela, Baertschi Alex J
Abstract excerpt
Cardiomyocytes express mRNA for all major subunits of ATP-sensitive potassium (K(ATP)) channels: KIR6.1, KIR6.2, SUR1A, SUR2A, and SUR2B. It has remained controversial as to whether KIR6.1 may associate with KIR6.2 to form the tetrameric pore of K(ATP) channels in cardiomyocytes. To explore this...
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