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Article

THE DNA REPLICATION FORK IN EUKARYOTIC CELLS

1 Jun 1998

Abstract excerpt

Replication of the two template strands at eukaryotic cell DNA replication forks is a highly coordinated process that ensures accurate and efficient genome duplication. Biochemical studies, principally of plasmid DNAs containing the Simian Virus 40 origin of DNA replication, and yeast genetic studies have uncovered the fundamental mechanisms of replication fork progression. At least two different DNA polymerases,...

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PMID: 9759502
DOI: 10.1146/annurev.biochem.67.1.721

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