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Article

Replication fork dynamics and the DNA damage response.

The Biochemical journal - 1 Apr 2012

Jones Rebecca M, Petermann Eva

Abstract excerpt

Prevention and repair of DNA damage is essential for maintenance of genomic stability and cell survival. DNA replication during S-phase can be a source of DNA damage if endogenous or exogenous stresses impair the progression of replication forks. It has become increasingly clear that DNA-damage-response pathways do not only respond to the presence of damaged DNA, but also modulate DNA replication dynamics to...

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Identifiers

PMID: 22417748
DOI: 10.1042/BJ20112100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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