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AAA+ ATPases in the Initiation of DNA Replication

1 Jan 2008

Abstract excerpt

All cellular organisms and many viruses rely on large, multi-subunit molecular machines, termed replisomes, to ensure that genetic material is accurately duplicated for transmission from one generation to the next. Replisome assembly is facilitated by dedicated initiator proteins, which serve to both recognize replication origins and recruit requisite replisomal components to the DNA in a cell-cycle coordinated...

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PMID: 18568846
DOI: 10.1080/10409230802058296

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