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Article

T cell-mediated exocrine pancreatic damage in major histocompatibility complex class II-deficient mice.

Gastroenterology - 1 Oct 1998

Vallance B A, Hewlett B R, Snider D P, Collins S M

Abstract excerpt

BACKGROUND & AIMS: Recent observations suggest a role for lymphocytes in human pancreatitis. However, existing animal models of pancreatitis are not immunologically based. In studies on major histocompatibility complex (MHC) II-deficient mice backcrossed five generations onto a C57BL/6 background, we discovered a progressive wasting disease due to pancreatic damage. The purpose of this study was to characterize...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9753501
DOI: 10.1016/s0016-5085(98)70270-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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