Article
New insights into the pathogenesis of pancreatitis.
Current opinion in gastroenterology - 1 Sept 2013
Sah Raghuwansh P, Dawra Rajinder K, Saluja Ashok K
Abstract excerpt
PURPOSE OF REVIEW: In this article, we review important advances in our understanding of the mechanisms of pancreatitis. RECENT FINDINGS: The relative contributions of intrapancreatic trypsinogen activation and nuclear factor kappa B (NFκB) activation, the two major early independent cellular events in pancreatitis, have been investigated using novel genetic models. Trypsinogen activation has traditionally held...
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