Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs.

Immunogenetics - 1 Jul 2013

Tsai Kate L, Starr-Moss Alison N, Venkataraman Gopalakrishnan M, Robinson Christopher, Kennedy Lorna J, Steiner Jörg M, Clark Leigh Anne

Abstract excerpt

Exocrine pancreatic insufficiency (EPI) is a disease wherein pancreatic acinar cells fail to synthesize and secrete sufficient amounts of digestive enzymes for normal digestion of food. EPI affects many dog breeds, with a dramatically higher prevalence in the German shepherd dog (GSD) population. In this breed and perhaps others, EPI most often results from degeneration of the acinar cells of the pancreas, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acinar Cells
Share to Atrophy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Autoimmune Diseases

Share to Dog Diseases

Share to Exocrine Pancreatic Insufficiency

Share to Histocompatibility Antigens Class I

Share to Sequence Homology

Source

Open in PubMed Open full text

Identifiers

PMID: 23604463
DOI: 10.1007/s00251-013-0704-y
PMCID: PMC3857963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs.PMID 23604463Read ↗

Current status of genetic studies of exocrine pancreatic insufficiency in dogs.Semantic proximity Read ↗

Association of DLA-DQB1 alleles with exocrine pancreatic insufficiency in Pembroke Welsh Corgis.Semantic proximity Read ↗

Identification of susceptibility and protective major histocompatibility complex haplotypes in canine diabetes mellitus.Semantic proximity Read ↗

Multiple autoimmune diseases syndrome in Italian Greyhounds: preliminary studies of genome-wide diversity and possible associations within the dog leukocyte antigen (DLA) complex.Semantic proximity Read ↗

Dog leukocyte antigen (DLA) class II genotypes associated with chronic enteropathy in French bulldogs and miniature dachshunds.Semantic proximity Read ↗

Organization of the canine major histocompatibility complex: current perspectivesSemantic proximity Read ↗

Dog leukocyte antigen genotyping across class I and class II genes in beagle dogs as laboratory animals.Semantic proximity Read ↗

DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel.Semantic proximity Read ↗

DLA class II risk haplotypes for autoimmune diseases in the bearded collie offer insight to autoimmunity signatures across dog breedsSemantic proximity Read ↗

PacBio long-read amplicon sequencing of dog leukocyte antigen genes at full-length level in beagle dogs.Semantic proximity Read ↗

Expanded dog leukocyte antigen (DLA) single nucleotide polymorphism (SNP) genotyping reveals spurious class II associations.Semantic proximity Read ↗

Thirteen novel canine dog leukocyte antigen-88 alleles identified by sequence-based typing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.