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Article

In vitro reconstitution of yeast splicing with U4 snRNA reveals multiple roles for the 3' stem-loop.

RNA (New York, N.Y.) - 1 May 2012

Hayduk Amy J, Stark Martha R, Rader Stephen D

Abstract excerpt

U4 small nuclear RNA (snRNA) plays a fundamental role in the process of premessenger RNA splicing, yet many questions remain regarding the location, interactions, and roles of its functional domains. To address some of these questions, we developed the first in vitro reconstitution system for yeast U4 small nuclear ribonucleoproteins (snRNPs). We used this system to examine the functional domains of U4 by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22411955
DOI: 10.1261/rna.031757.111
PMCID: PMC3334694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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