Article

Novel function of U7 snRNA in the repression of HERV1/LTR12s and lincRNAs in human cells

2023-08-26

Abstract excerpt

<h4>ABSTRACT</h4> U7 snRNA is part of U7 snRNP, a complex required for the 3’end processing of replication-dependent histone pre-mRNAs in the S phase of the cell cycle. During this maturation event, the 5’ region of U7 snRNA hybridizes with the highly complementary sequence present in the 3’UTR of histone pre-mRNAs, called histone downstream element, HDE. This base-pair interaction triggers subsequent reactions t...

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Literature Corpus work: 6f1c8a3a-00b1-53be-8b5d-2cb20075e057
DOI: 10.1101/2023.08.25.554787

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