Article
A U6 snRNA gene with an internal promoter is juxtaposed to an snRNP protein sequence within an intron of a human G protein gene.
Nucleic acids research - 11 Jun 1991
Wieben E D, Vrabel A M, Holicky E L, Klisak I, Sparkes R S, Stanford D R
Abstract excerpt
A complex locus on human chromosome 1 brings together sequences homologous to a G protein and two components of the RNA processing machinery of eukaryotic cells. Specifically, the seventh intron of the human Gi3 alpha gene contains a fusion of a partial snRNP E protein pseudogene to a variant U6...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- GTP-Binding Proteins
- Humans
- Introns
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Promoter Regions, Genetic
- Pseudogenes
- RNA, Small Nuclear
- Ribonucleoproteins