Article
An ATP-ADP switch in MuB controls progression of the Mu transposition pathway.
The EMBO journal - 15 Sept 1998
Yamauchi M, Baker T A
Abstract excerpt
MuB protein, an ATP-dependent DNA-binding protein, collaborates with Mu transposase to promote efficient transposition. MuB binds target DNA, delivers this target DNA segment to transposase and activates transposase's catalytic functions. Using ATP-bound, ADP-bound and ATPase-defective MuB protei...
Topics
- Adenosine Diphosphate
- Adenosine Triphosphatases
- Adenosine Triphosphate
- Bacteriophage mu
- DNA Transposable Elements
- DNA, Viral
- DNA-Binding Proteins
- Hydrolysis
- Mutation
- Recombination, Genetic
- Transposases
- Viral Proteins