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Article

Complete transposition requires four active monomers in the mu transposase tetramer.

Genes & development - 15 Oct 1994

Baker T A, Kremenstova E, Luo L

Abstract excerpt

A tetramer of Mu transposase (MuA) cleaves and joins multiple DNA strands to promote transposition. Derivatives of MuA altered at two acidic residues that are conserved among transposases and retroviral integrases form tetramers but are defective in both cleavage and joining. These mutant proteins were used to analyze the contribution of individual monomers to the activity of the tetramer. The performance of...

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Identifiers

PMID: 7958906
DOI: 10.1101/gad.8.20.2416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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