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Article

CLB5-dependent activation of late replication origins in S. cerevisiae.

Molecular cell - 1 Aug 1998

Donaldson A D, Raghuraman M K, Friedman K L, Cross F R, Brewer B J, Fangman W L

Abstract excerpt

Replication origins in chromosomes are activated at specific times during the S phase. We show that the B-type cyclins are required for proper execution of this temporal program. clb5 cells activate early origins but not late origins, explaining the previously described long clb5 S phase. Origin...

Topics

Chromosomes, Fungal
Cyclin B
Cyclins
DNA Replication
DNA, Fungal
Fungal Proteins
Kinetics
Models, Biological
Mutation
Replication Origin
S Phase
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9734354
DOI: 10.1016/s1097-2765(00)80127-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9734354-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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