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Article

CLB5: a novel B cyclin from budding yeast with a role in S phase.

Genes & development - 1 Sept 1992

Epstein C B, Cross F R

Abstract excerpt

Budding yeast strains have three CLN genes, which have limited cyclin homology. At least one of the three is required for cell cycle START. Four B cyclins are known in yeast; two have been shown to function in mitosis. We have discovered a fifth B-cyclin gene, called CLB5, which when cloned on a CEN plasmid can rescue strains deleted for all three CLN genes. CLB5 transcript abundance peaks in G1, coincident with...

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Source

Identifiers

PMID: 1387626
DOI: 10.1101/gad.6.9.1695

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CLB5: a novel B cyclin from budding yeast with a role in S phase.PMID 1387626Read ↗

Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.Semantic proximity Read ↗

Among B-type cyclins only CLB5 and CLB6 promote premeiotic S phase in Saccharomyces cerevisiae.Semantic proximity Read ↗

Negative regulation of G1 and G2 by S-phase cyclins of Saccharomyces cerevisiae.Semantic proximity Read ↗

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.Semantic proximity Read ↗

Functional distinction between Cln1p and Cln2p cyclins in the control of the Saccharomyces cerevisiae mitotic cycle.Semantic proximity Read ↗

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae.Semantic proximity Read ↗

Clb5-associated kinase activity is required early in the spindle pathway for correct preanaphase nuclear positioning in Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast mitotic cyclin Clb2 cannot substitute for S phase cyclins in replication origin firing.Semantic proximity Read ↗

Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6.Semantic proximity Read ↗

Differential cellular localization among mitotic cyclins from Saccharomyces cerevisiae: a new role for the axial budding protein Bud3 in targeting Clb2 to the mother-bud neck.Semantic proximity Read ↗

CLB5-dependent activation of late replication origins in S. cerevisiae.Semantic proximity Read ↗

Conservation and function of a potential substrate-binding domain in the yeast Clb5 B-type cyclin.Semantic proximity Read ↗

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