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Article

Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae.

The Journal of biological chemistry - 11 Sept 1998

Martins L J, Jensen L T, Simon J R, Keller G L, Winge D R, Simons J R

Abstract excerpt

The high affinity uptake systems for iron and copper ions in Saccharomyces cerevisiae involve metal-specific permeases and two known cell surface Cu(II) and Fe(III) metalloreductases, Fre1 and Fre2. Five novel genes found in the S. cerevisiae genome exhibit marked sequence similarity to Fre1 and Fre2, suggesting that the homologs are part of a family of proteins related to Fre1 and Fre2. The homologs are...

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PMID: 9726978
DOI: 10.1074/jbc.273.37.23716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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