Article
Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1.
The Journal of biological chemistry - 11 Jul 1997
Yamaguchi-Iwai Y, Serpe M, Haile D, Yang W, Kosman D J, Klausner R D, Dancis A
Abstract excerpt
Copper deprivation of Saccharomyces cerevisiae induces transcription of the FRE1 and CTR1 genes. FRE1 encodes a surface reductase capable of reducing and mobilizing copper chelates outside the cell, and CTR1 encodes a protein mediating copper uptake at the plasma membrane. In this paper, the prot...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cation Transport Proteins
- Copper
- Copper Transporter 1
- DNA, Fungal
- FMN Reductase
- Fungal Proteins
- Homeostasis
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- NADH, NADPH Oxidoreductases
- Nuclear Proteins