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Article

Exploratory and confirmatory gene expression profiling of mac1Delta.

The Journal of biological chemistry - 6 Feb 2004

De Freitas Jeane Maria, Kim Jeung Hyoun, Poynton Helen, Su Trent, Wintz Henri, Fox Tama, Holman Patty, Loguinov Alex, Keles Sunduz, van der Laan Mark, Vulpe Chris

Abstract excerpt

Exploratory outlier identification methods and confirmatory gene expression studies showed induction of the iron regulon in Saccharomyces cerevisiae lacking Mac1p, a copper-responsive transcription factor. The Aft1p/Aft2p binding motif was the most discriminating motif between up- and down-regulated genes, and we identified new genes potentially regulated by Aft1p/Aft2p. In addition, multiple genes encoding...

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PMID: 14534306
DOI: 10.1074/jbc.M212308200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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