Article
The Fe(II) permease Fet4p functions as a low affinity copper transporter and supports normal copper trafficking in Saccharomyces cerevisiae.
The Biochemical journal - 15 Oct 2000
Hassett R, Dix D R, Eide D J, Kosman D J
Abstract excerpt
The plasma-membrane of Saccharomyces cerevisiae contains high affinity permeases for Cu(I) and Fe(II). A low affinity Fe(II) permease has also been identified, designated Fet4p. A corresponding low affinity copper permease has not been characterized, although yeast cells that lack high affinity copper uptake do accumulate this metal ion. We demonstrate in the present study that Fet4p can function as a low...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.