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Article

AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae.

The EMBO journal - 15 Mar 1995

Yamaguchi-Iwai Y, Dancis A, Klausner R D

Abstract excerpt

Using a scheme for selecting mutants of Saccharomyces cerevisiae with abnormalities of iron metabolism, we have identified a gene, AFT1, that mediates the control of iron uptake. AFT1 encodes a 78 kDa protein with a highly basic amino terminal domain and a glutamine-rich C-terminal domain, reminiscent of transcriptional activators. The protein also contains an amino terminal and a C-terminal region with 10% His...

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Identifiers

PMID: 7720713
DOI: 10.1002/j.1460-2075.1995.tb07106.x
PMCID: PMC398200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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