Article
AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae.
The EMBO journal - 15 Mar 1995
Yamaguchi-Iwai Y, Dancis A, Klausner R D
Abstract excerpt
Using a scheme for selecting mutants of Saccharomyces cerevisiae with abnormalities of iron metabolism, we have identified a gene, AFT1, that mediates the control of iron uptake. AFT1 encodes a 78 kDa protein with a highly basic amino terminal domain and a glutamine-rich C-terminal domain, remini...
Topics
- Amino Acid Sequence
- Base Sequence
- Biological Transport
- Ceruloplasmin
- Cloning, Molecular
- FMN Reductase
- Ferrous Compounds
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Homeostasis
- Molecular Sequence Data
- Mutation
- NADH, NADPH Oxidoreductases
- Oxidoreductases
- RNA, Fungal
- RNA, Messenger
- Restriction Mapping