Article
The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake.
The Journal of biological chemistry - 14 Oct 1994
Dancis A, Haile D, Yuan D S, Klausner R D
Abstract excerpt
The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and exists as an oligomer in vivo. The transcript abundance is strongly regulated by copper availability,...
Topics
- Aerobiosis
- Base Sequence
- Biological Transport
- Carrier Proteins
- Cation Transport Proteins
- Copper
- Copper Transporter 1
- Cytosol
- FMN Reductase
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Reporter
- Homeostasis
- Membrane Proteins
- Metallothionein
- Molecular Sequence Data
- NADH, NADPH Oxidoreductases