Article
Characterization of human TCR Vbeta gene promoter. Role of the dodecamer motif in promoter activity.
The Journal of biological chemistry - 11 Sept 1998
Deng X, Sun G R, Zheng Q, Li Y
Abstract excerpt
During T-lymphocyte development, the T-cell antigen receptor (TCR) gene expression is controlled by its promoter and enhancer elements and regulated in tissue- and development stage-specific manner. To uncover the promoter function and to define positive and negative regulatory elements in TCR gene promoters, the promoter activities from 13 human TCR Vbeta genes were determined by the transient transfection...
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