Article
Identification and characterization of the human transforming growth factor-alpha initiator.
Molecular endocrinology (Baltimore, Md.) - 1 Jun 1994
Shin T H, Kudlow J E
Abstract excerpt
Eukaryotic transcription requires promoter proximal elements. For class II promoters, two such elements are the TATA box and the initiator. The promoter for the human transforming growth factor-alpha (TGF alpha) gene has been shown to lack a TATA box, yet initiate transcription at a unique site. We have identified an approximately 13-basepair sequence between -5 and +8 as a new promoter element. We call this...
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