Article
Genomic organization and characterization of the promoter for the E2A gene.
Gene - 21 Jan 2004
Hata Kikumi, Mizuguchi Junichiro
Abstract excerpt
Although E2A gene products are ubiquitously expressed, E2A-deficient mice display selective abnormalities in lymphocyte development, suggesting a certain requirement of the E2A gene products during lymphocyte development. To gain insights into the mechanisms of E2A transcriptional regulation, we isolated the genomic clones which are composed of four exons and one noncoding exon and span approximately 16 kb. The...
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