Article
The role of viral enhancer "core" motif-related sequences in regulating T cell receptor-gamma and -delta gene expression.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 1993
Hsiang Y H, Spencer D, Wang S, Speck N A, Raulet D H
Abstract excerpt
T cells express clonally distributed alpha beta or gamma delta Ag receptor heterodimers. Transcriptional enhancers for the genes of all four subunits are active in both gamma delta and alpha beta T cells, but are less active or inactive in other cells. Conserved sequence motifs are present in all four enhancers, suggesting that common transcription factors regulate TCR gene expression. One of these motifs in the...
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