Article
Multiple cis-acting elements are required for proper transcription of the mouse V delta 1 T cell receptor promoter.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 1993
Punturieri A, Shirakata Y, Bovolenta C, Kikuchi G, Coligan J E
Abstract excerpt
To gain insight into the developmentally regulated expression of the mouse TCR V delta-gene segments, we have investigated the role of the 5' promoter region of the V delta 1-gene. Transient transfection assays showed that a construct encompassing 267 nucleotides upstream from the mapped transcriptional start site was capable of driving promoter activity when transfected into V delta 1+ T cells. The inclusion of...
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