Article
No relationship between identified variants in the uncoupling protein 2 gene and energy expenditure.
European journal of endocrinology - 1 Aug 1998
Klannemark M, Orho M, Groop L
Abstract excerpt
OBJECTIVE: The uncoupling protein 2 (UCP2) uncouples respiration from the oxidative phosphorylation in most cell types, predominantly in white fat and skeletal muscle. Since a decreased basal metabolic rate (BMR) would increase the susceptibility to weight gain, genetic alterations in the UCP2 ge...
Topics
- Aged
- Alanine
- Amino Acid Substitution
- Energy Metabolism
- Exons
- Female
- Genetic Variation
- Genotype
- Humans
- Introns
- Ion Channels
- Male
- Membrane Transport Proteins
- Middle Aged
- Mitochondrial Proteins
- Molecular Sequence Data
- Obesity
- Polymorphism, Single-Stranded Conformational