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Article

Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians.

Diabetologia - 1 Nov 2005

Kovacs P, Ma L, Hanson R L, Franks P, Stumvoll M, Bogardus C, Baier L J

Abstract excerpt

AIMS/HYPOTHESIS: Uncoupling protein-2 (UCP2) is thought to play a role in insulin secretion and the development of obesity. In this study, we investigated the effects of genetic variation in UCP2 on type 2 diabetes and obesity, as well as on metabolic phenotypes related to these diseases, in Pima Indians. METHODS: The coding and untranslated regions of UCP2, and approximately 1 kb of the 5' upstream region, were...

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Source

Identifiers

PMID: 16167150
DOI: 10.1007/s00125-005-1934-9

Genes

UCP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians.PMID 16167150Read ↗

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Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion.Semantic proximity Read ↗

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The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.Semantic proximity Read ↗

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