Analysis of the uncoupling protein-1 (UCP1) gene in obese and lean subjects: identification of four amino acid variants.

doi:10.1038/sj.ijo.0800725

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Article

Analysis of the uncoupling protein-1 (UCP1) gene in obese and lean subjects: identification of four amino acid variants.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Sept 1998

Hamann A, Tafel J, Büsing B, Münzberg H, Hinney A, Mayer H, Siegfried W, Ricquier D, Greten H, Hebebrand J, Matthaei S

Abstract excerpt

Uncoupling protein-1 (UCP1) is uniquely expressed in brown adipose tissue (BAT) and of major importance for the tissues thermogenic capacity. This study was undertaken to detect variants in the UCP1 gene by single strand conformational polymorphism (SSCP) analysis and subsequent sequencing, and d...

Topics

Adolescent
Adult
Alleles
Body Mass Index
Carrier Proteins
Child
Cohort Studies
Female
Gene Frequency
Humans
Ion Channels
Male
Membrane Proteins
Mitochondrial Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Obesity

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 9756256
DOI: 10.1038/sj.ijo.0800725

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9756256-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.